restless legs syndrome

Meaning of restless legs syndrome: The hallmark of restless legs syndrome is an urge to move the legs that relieves an uncomfortable sensation, worsening at rest and in the evening.

Definition of restless legs syndrome

Restless legs syndrome is a neurological condition marked by an uncomfortable sensation in the legs, described variously as crawling, tingling, itching, or aching, paired with a strong urge to move the legs that partly or fully relieves the feeling. Similar sensations can occasionally involve the arms or other body parts as well.

Symptoms characteristically occur or worsen during periods of rest or inactivity, such as sitting or lying down, and tend to be more pronounced in the evening or at night, which can interfere with falling asleep. Movement, such as walking or stretching, typically brings at least temporary relief.

Restless legs syndrome can occur on its own or alongside another condition, including iron deficiency, kidney disease, or pregnancy, and it is also known as Willis-Ekbom disease. Its nighttime pattern and clear relationship to movement distinguish it from other causes of leg discomfort, such as circulation problems or nerve irritation, which do not typically improve with motion in the same way.

Also known as

Willis-Ekbom disease

Used in a sentence

The patient described a recurring urge to move the legs at night, consistent with restless legs syndrome.

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Good to know

Restless legs syndrome is sometimes mistaken for simple leg cramps or poor circulation, though its defining feature, an urge to move that is relieved by movement and worsens with rest, distinguishes it from those other causes of leg discomfort.

Word origin

Where “restless legs syndrome” comes from

Formed from Greek syn- (together) and dromos (running), the root of syndrome, describing a group of symptoms that occur together as a recognizable pattern.

For learning, not diagnosis. This glossary provides general educational information and is not a substitute for advice from a qualified healthcare professional. If you may be experiencing a medical emergency, contact local emergency services.