prostaglandin-endoperoxide synthase 2

Meaning of prostaglandin-endoperoxide synthase 2: An enzyme that speeds up the formation of substances that cause inflammation and pain.

Definition of prostaglandin-endoperoxide synthase 2

An enzyme that speeds up the formation of substances that cause inflammation and pain. It may also cause tumor cells to grow. Some tumors have high levels of prostaglandin-endoperoxide synthase 2 and blocking its activity may reduce tumor growth. Also called COX-2 and cyclooxygenase-2.