perillyl alcohol

Meaning of perillyl alcohol: A naturally occurring monoterpene related to limonene with antineoplastic activity.

Definition of perillyl alcohol

A naturally occurring monoterpene related to limonene with antineoplastic activity. Perillyl alcohol inhibits farnesyl transferase and geranylgeranyl transferase, thereby preventing post-translational protein farnesylation and isoprenylation and activation of oncoproteins such as p21-ras, and arresting tumor cells in the G1 phase of the cell cycle.

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