MedicalTerminology DB

Meaning of PCNSL: Primary CNS lymphoma.

Definition of PCNSL

Primary CNS lymphoma. Cancer that forms in the lymph tissue of the brain, spinal cord, meninges (outer covering of the brain), or eye (called ocular lymphoma). Also called primary central nervous system lymphoma and primary CNS lymphoma.

Written and maintained by James Murray Last updated July 21, 2026 Educational reference, not medical advice. Read the limitations.

For learning, not diagnosis. This glossary provides general educational information and is not a substitute for advice from a qualified healthcare professional. If you may be experiencing a medical emergency, contact local emergency services.