MedicalTerminology DB

Meaning of palmar-plantar erythrodysesthesia: A condition marked by pain, swelling, numbness, tingling, or redness of the hands or feet.

Definition of palmar-plantar erythrodysesthesia

A condition marked by pain, swelling, numbness, tingling, or redness of the hands or feet. It sometimes occurs as a side effect of certain anticancer drugs. Also called hand-foot syndrome.

Written and maintained by James Murray Last updated July 21, 2026 Educational reference, not medical advice. Read the limitations.

For learning, not diagnosis. This glossary provides general educational information and is not a substitute for advice from a qualified healthcare professional. If you may be experiencing a medical emergency, contact local emergency services.