granisetron hydrochloride

Definition / meaning of granisetron hydrochloride

The hydrochloride salt of an indazole derivative with antiemetic properties. As a selective serotonin receptor antagonist, granisetron competitively blocks the action of serotonin at 5-hydroxytryptamine3 (5-HT3) receptors, resulting in the suppression of chemotherapy- and radiotherapy-induced nausea and vomiting.

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Source(s):

The Web site of the National Cancer Institute (http://www.cancer.gov/)

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