fluorescence in situ hybridization

Meaning of fluorescence in situ hybridization: A laboratory technique used to look at genes or chromosomes in cells and tissues.

Definition of fluorescence in situ hybridization

A laboratory technique used to look at genes or chromosomes in cells and tissues. Pieces of DNA that contain a fluorescent dye are made in the laboratory and added to cells or tissues on a glass slide. When these pieces of DNA bind to specific genes or areas of chromosomes on the slide, they light up when viewed under a microscope with a special light. Also called fluorescence in situ hybridization.