endothelin-1 protein receptor antagonist

Definition / meaning of endothelin-1 protein receptor antagonist

A substance that blocks the binding of the endothelin-1 protein to its receptor. Endothelin-1 is a small molecule that causes changes in blood vessels and helps regulate blood pressure. It can also stimulate the growth of some types of cells.

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The Web site of the National Cancer Institute (http://www.cancer.gov/)

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