Definition / meaning of emtricitabine

A synthetic nucleoside analogue of cytidine with activity against human immunodeficiency virus type 1 reverse transcriptase (RT). Emtricitabine is phosphorylated by cellular enzymes to form emtricitabine 5′-triphosphate. Emtricitabine 5′-triphosphate inhibits the activity of HIV-1 RT by competing with the RT natural substrate deoxycytidine 5′-triphosphate and by being incoprorated into nascent viral DNA which results in the termination of viral DNA chain elongation.

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Find More About 'emtricitabine'


The Web site of the National Cancer Institute (http://www.cancer.gov/)

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