Definition / meaning of elsamitrucin

A heterocyclic antineoplastic antibiotic isolated from the bacterium Actinomycete strain J907-21. Elsamitrucin intercalates into DNA at guanine-cytosine (G-C)-rich sequences and inhibits topoisomerase I and II, resulting in single-strand breaks and inhibition of DNA replication.

Listed under:

Find More About 'elsamitrucin'


The Web site of the National Cancer Institute (http://www.cancer.gov/)

Leave a Comment


This site uses Akismet to reduce spam. Learn how your comment data is processed.