diethylstilbestrol

Definition / meaning of diethylstilbestrol

DES; the acronym for diethylstilbestrol, a synthetic, nonsteroidal form of estrogen. A well-known teratogen and carcinogen, DES inhibits the hypothalamic-pituitary-gonadal axis, thereby blocking the testicular synthesis of testosterone, lowering plasma testosterone, and inducing a chemical castration.

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Find More About 'diethylstilbestrol'

Source(s):

The Web site of the National Cancer Institute (http://www.cancer.gov/)

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