Home/Topics/Cancer & Tumors/Clark level V melanoma Cancer & Tumors Cancer & Oncology Skin, Hair & Nails Clark level V melanoma Listen Save Share Print Meaning of Clark level V melanoma: Melanoma that has spread down into the subcutaneous tissue (tissue beneath the skin). Definition of Clark level V melanoma Melanoma that has spread down into the subcutaneous tissue (tissue beneath the skin). Written and maintained by James Murray · Last updated July 21, 2026 Educational reference, not medical advice. Read the limitations. Keep exploringRelated termsMore in Cancer & Tumors → Cancer & Tumors melanoma Far less common than the everyday skin cancers but responsible for most deaths from them, because it spreads while it is still small. Read definition → Cancer & Tumors skin cancer One label covers several different diseases, and which cell a tumor came from matters far more than the fact that it sits in skin. Read definition → Cancer & Tumors amelanotic melanoma Amelanotic melanoma is a form of skin cancer that lacks the dark pigment typical of melanoma, often appearing pink or red instead. Read definition → Cancer & Tumors hairy cell leukemia A slow-growing blood cancer named for the fringed look of its cells, marked by a large spleen and low counts across the board. Read definition →
Cancer & Tumors melanoma Far less common than the everyday skin cancers but responsible for most deaths from them, because it spreads while it is still small. Read definition →
Cancer & Tumors skin cancer One label covers several different diseases, and which cell a tumor came from matters far more than the fact that it sits in skin. Read definition →
Cancer & Tumors amelanotic melanoma Amelanotic melanoma is a form of skin cancer that lacks the dark pigment typical of melanoma, often appearing pink or red instead. Read definition →
Cancer & Tumors hairy cell leukemia A slow-growing blood cancer named for the fringed look of its cells, marked by a large spleen and low counts across the board. Read definition →