Definition / meaning of cCLB8

A chimeric (made from human and mouse proteins) monoclonal antibody being studied in the treatment of advanced kidney cancer and other types of cancer. Monoclonal antibodies are made in the laboratory and can locate and bind to substances in the body, including cancer cells. cCLB8 works by blocking inflammation and tumor growth. Also called anti-IL-6 chimeric monoclonal antibody and CNTO 328.

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The Web site of the National Cancer Institute (

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