MedicalTerminology DB
Cancer & Tumors Cancer & Oncology

carcinoma of unknown primary

Meaning of carcinoma of unknown primary: A case in which cancer cells are found in the body, but the place where the cells first started growing (the origin or primary site) cannot be determined.

Definition of carcinoma of unknown primary

A case in which cancer cells are found in the body, but the place where the cells first started growing (the origin or primary site) cannot be determined. Also called cancer of unknown primary origin and CUP.

Written and maintained by James Murray Last updated July 21, 2026 Educational reference, not medical advice. Read the limitations.

For learning, not diagnosis. This glossary provides general educational information and is not a substitute for advice from a qualified healthcare professional. If you may be experiencing a medical emergency, contact local emergency services.