bupivacaine hydrochloride

Definition / meaning of bupivacaine hydrochloride

A long-acting, amide-type local anesthetic. Bupivicaine reversibly binds to specific sodium ion channels in the neuronal membrane, resulting in a decrease in the voltage-dependent membrane permeability to sodium ions and membrane stabilization; inhibition of depolarization and nerve impulse conduction; and a reversible loss of sensation.

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Source(s):

The Web site of the National Cancer Institute (http://www.cancer.gov/)

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