autologous lymphoma cell lysate-pulsed autologous dendritic cell vaccine

Definition / meaning of autologous lymphoma cell lysate-pulsed autologous dendritic cell vaccine

A cell-based cancer vaccine composed of autologous dendritic cells (DCs) pulsed with lysate from autologous lymphoma cells with potential immunostimulatory and antineoplastic activities. Upon intranodal administration, autologous lymphoma cell lysate-pulsed autologous DC vaccine may stimulate the immune system to mount anti-tumoral cytotoxic T lymphocyte (CTL) and antibody responses against lymphoma cells, which may result in lymphoma cell lysis.

Listed under:

Find More About 'autologous lymphoma cell lysate-pulsed autologous dendritic cell vaccine'

Source(s):

The Web site of the National Cancer Institute (http://www.cancer.gov/)

Leave a Comment