atypical squamous cells of undetermined significance

Meaning of atypical squamous cells of undetermined significance: Abnormal cells from the outer walls of the cervix (the lower, narrow end of the uterus).

Definition of atypical squamous cells of undetermined significance

Abnormal cells from the outer walls of the cervix (the lower, narrow end of the uterus). Abnormal squamous cells (thin, flat cells that look like fish scales) are found in a low number of Pap smears (a procedure used to detect cervical cancer) and may indicate infection with the human papillomavirus (HPV) or another infectious agent. The risk of developing cervical cancer is very low for patients with atypical squamous cells of undetermined significance without HPV infection. Also called ASC-US and ASCUS.

For learning, not diagnosis. This glossary provides general educational information and is not a substitute for advice from a qualified healthcare professional. If you may be experiencing a medical emergency, contact local emergency services.