Definition / meaning of 17-N-allylamino-17-demethoxygeldanamycin

A substance being studied in the treatment of cancer. It is made from an antibiotic called geldanamycin. 17-N-allylamino-17-demethoxygeldanamycin helps cause the breakdown of certain proteins in the cell, and may kill cancer cells. It is a type of antineoplastic antibiotic and a type of HSP90 inhibitor. Also called 17-AAG and tanespimycin.

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The Web site of the National Cancer Institute (http://www.cancer.gov/)

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