Z-360

Definition / meaning of Z-360

A selective, orally available, 1,5-benzodiazepine-derivative gastrin/cholecystokinin 2 (CCK-2) receptor antagonist with potential antineoplastic activity. Z-360 binds to the gastrin/CCK-2 receptor, thereby preventing receptor activation by gastrin, a peptide hormone frequently associated with the proliferation of gastrointestinal and pancreatic tumor cells.

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Find More About 'Z-360'

Source(s):

The Web site of the National Cancer Institute (http://www.cancer.gov/)

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