yttrium Y 90 monoclonal antibody B3

Definition / meaning of yttrium Y 90 monoclonal antibody B3

A radioimmunoconjugate of monoclonal antibody (MoAb) B3 conjugated with isotope yttrium 90. MoAb B3 is a murine MoAb that recognizes a Lewis Y carbohydrate antigen present on the surface of many carcinomas. This radioimmunoconjugate emits beta particles that causes cytotoxicity in tumor cells and has both diagnostic and therapeutic uses.

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Source(s):

The Web site of the National Cancer Institute (http://www.cancer.gov/)

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