PSA:154-163(155L) peptide vaccine

Definition / meaning of PSA:154-163(155L) peptide vaccine

A cancer vaccine comprised of a synthetic peptide with an amino acid sequence corresponding to positions 154-163 of the amino acid sequence for prostate-specific antigen (PSA) with a leucine substitution at position 155. Upon administration, PSA:154-163(155L) peptide vaccine may elicit a cytotoxic T-cell response against tumor cells that express PSA.

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Source(s):

The Web site of the National Cancer Institute (http://www.cancer.gov/)

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