prostatic acid phosphatase-sargramostim fusion protein

Definition / meaning of prostatic acid phosphatase-sargramostim fusion protein

A genetically-engineered protein formed by the fusion of prostatic acid phosphatase (PAP) and sargramostim (GM-CSF). Vaccination with antigen-presenting cells (APC) loaded with prostatic acid phosphatase-sargramostim fusion protein may elicit a cytotoxic T-cell response against tumor cells that express PAP.

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Source(s):

The Web site of the National Cancer Institute (http://www.cancer.gov/)

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