prostaglandin-endoperoxide synthase 2

Definition / meaning of prostaglandin-endoperoxide synthase 2

An enzyme that speeds up the formation of substances that cause inflammation and pain. It may also cause tumor cells to grow. Some tumors have high levels of prostaglandin-endoperoxide synthase 2 and blocking its activity may reduce tumor growth. Also called COX-2 and cyclooxygenase-2.

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Source(s):

The Web site of the National Cancer Institute (http://www.cancer.gov/)

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