prochlorperazine

Definition / meaning of prochlorperazine

A synthetic propylpiperazine derivative of phenothiazine with antiemetic, antipsychotic, antihistaminic, and anticholinergic activities. Prochlorperazine antagonizes the dopamine D2-receptor in the chemoreceptor trigger zone (CTZ) of the brain and may prevent chemotherapy-induced emesis.

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Source(s):

The Web site of the National Cancer Institute (http://www.cancer.gov/)

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