povidone-iodine solution

Definition / meaning of povidone-iodine solution

An iodophor solution containing a water-soluble complex of iodine and polyvinylpyrrolidone (PVP) with broad microbicidal activity. Free iodine, slowly liberated from the povoiodine-iodine (PVPI) complex in solution, kills eukaryotic or prokaryotic cells through iodination of lipids and oxidation of cytosplasmic and membrane compounds. This agent exhbits a broad range of microbicidal activity against bacteria, fungi, protozoa, and viruses.Slow release of iodine from the PVPI complex in solution minimizes iodine toxicity towards mammalian cells.

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The Web site of the National Cancer Institute (http://www.cancer.gov/)

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