post-transplant lymphoproliferative disorder

Definition / meaning of post-transplant lymphoproliferative disorder

A condition in which a group of B-cells grow out of control after an organ transplant in patients with weakened immune systems. This usually happens if the patient has also been infected with Epstein-Barr virus. Post-transplant lymphoproliferative disorder may progress to non-Hodgkin lymphoma. Also called PTLD.

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Source(s):

The Web site of the National Cancer Institute (http://www.cancer.gov/)

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