pixantrone dimaleate

Definition / meaning of pixantrone dimaleate

The dimaleate salt of a synthetic, noncardiotoxic aza-anthracenedione analogue with potential antineoplastic activity. Pixantrone intercalates into DNA and induces topoisomerase II-mediated DNA strand crosslinks, resulting in inhibition of DNA replication and tumor cell cytotoxicity.

Listed under:

Find More About 'pixantrone dimaleate'

Source(s):

The Web site of the National Cancer Institute (http://www.cancer.gov/)

Leave a Comment

*