picoplatin

Definition / meaning of picoplatin

A new generation organic platinum analog with an extended spectrum of antineoplastic activity. Designed to overcome platinum drug resistance, picoplatin alkylates DNA, forming both inter- and intra-strand cross-linkages, resulting in inhibition of DNA replication and transcription, and the induction of apoptosis.

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Source(s):

The Web site of the National Cancer Institute (http://www.cancer.gov/)

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