panitumumab

Definition / meaning of panitumumab

A human monoclonal antibody produced in transgenic mice that attaches to the transmembrane epidermal growth factor (EGF) receptor. Panitumumab may inhibit autocrine EGF stimulation of tumor cells that express the EGF receptor, thereby inhibiting tumor cell proliferation.

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Source(s):

The Web site of the National Cancer Institute (http://www.cancer.gov/)

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