palladium-bacteriopheophorbide

Definition / meaning of palladium-bacteriopheophorbide

A novel palladium-substituted bacteriochlorophyll derivative and photosensitizer with potential antitumor activity. Upon administration, inactive palladium-bacteriophephorbide is activated locally when the tumor bed is exposed to photoirradiation; the activated form induces local cytotoxic processes, resulting in local tissue damage, disruption of tumor vasculature, and tumor hypoxia and necrosis.

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Source(s):

The Web site of the National Cancer Institute (http://www.cancer.gov/)

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