Paget disease of bone

Definition / meaning of Paget disease of bone

A chronic condition in which both the breakdown and regrowth of bone are increased. Paget disease of bone occurs most frequently in the pelvic and leg bones, skull, and lower spine. It is most common in older individuals, and may lead to bone pain, deformities, and fractures. Also called osteitis deformans.

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Source(s):

The Web site of the National Cancer Institute (http://www.cancer.gov/)

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