OGX-011

Definition / meaning of OGX-011

A substance being studied in the treatment of cancer. It blocks the production of a protein called clusterin, which helps cells live longer. This may kill cancer cells that need clusterin to grow. It may also make cells more sensitive to anticancer drugs. It is a type of antisense oligonucleotide, and a type of chemosensitizing agent. Also called custirsen sodium.

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Source(s):

The Web site of the National Cancer Institute (http://www.cancer.gov/)

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