ofloxacin

Definition / meaning of ofloxacin

A fluoroquinolone antibacterial antibiotic. Ofloxacin binds to and inhibits bacterial topoisomerase II (DNA gyrase) and topoisomerase IV, enzymes involved in DNA replication and repair, resulting in cell death in sensitive bacterial species.

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Source(s):

The Web site of the National Cancer Institute (http://www.cancer.gov/)

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