lestaurtinib

Definition / meaning of lestaurtinib

An orally bioavailable indolocarbazole derivative with antineoplastic properties. Lestaurtinib inhibits autophosphorylation of FMS-like tyrosine kinase 3 (FLT3), resulting in inhibition of FLT3 activity and induction of apoptosis in tumor cells that overexpress FLT3.

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Find More About 'lestaurtinib'

Source(s):

The Web site of the National Cancer Institute (http://www.cancer.gov/)

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