ketamine hydrochloride

Definition / meaning of ketamine hydrochloride

The hydrochloride salt of a synthetic derivative of cyclohexanone with analgesic and anesthetic activities. Although its mechanism of action is not well understood, ketamine appears to non-competitively block N-methyl-D-aspartate (NMDA) receptors and may interact with opiod mu receptors and sigma receptors, thereby reducing pain perception, inducing sedation, and producing dissociative anesthesia.

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The Web site of the National Cancer Institute (http://www.cancer.gov/)

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