iodine I 131 chimeric monoclonal antibody G-250

Definition / meaning of iodine I 131 chimeric monoclonal antibody G-250

A radioimmunoconjugate comprised of the chimeric monoclonal antibody G-250 conjugated with iodine I 131 with potential antineoplastic activity. The antibody moiety of iodine I 131 chimeric monoclonal antibody G-250 binds to G-250, a renal-cell carcinoma-associated antigen, delivering cytotoxic iodine I 131 specifically to renal cell carcinoma cells that express G-250.

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Source(s):

The Web site of the National Cancer Institute (http://www.cancer.gov/)

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