imiquimod

Definition / meaning of imiquimod

A synthetic agent with immune response modifying activity. As an immune response modifier (IRM), imiquimod stimulates cytokine production, especially interferon production, and exhibits antitumor activity, particularly against cutaneous cancers. Imiquimod’s proapoptotic activity appears to be related to Bcl-2 overexpression in susceptible tumor cells.

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Source(s):

The Web site of the National Cancer Institute (http://www.cancer.gov/)

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