grade IV astrocytoma

Definition / meaning of grade IV astrocytoma

A fast-growing type of central nervous system tumor that forms from glial (supportive) tissue of the brain and spinal cord and has cells that look very different from normal cells. Grade IV astrocytoma usually occurs in adults and affects the brain more often than the spinal cord. Also called GBM, glioblastoma, and glioblastoma multiforme.

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