GPX-100

Definition / meaning of GPX-100

An analogue of the anthracycline antineoplastic antibiotic doxorubicin. GPX-100 intercalates DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair and RNA and protein synthesis. GPX-100 was designed to be a non-cardiotoxic anthracycline antibiotic.

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Find More About 'GPX-100'

Source(s):

The Web site of the National Cancer Institute (http://www.cancer.gov/)

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