gp100:154-162 peptide vaccine

Definition / meaning of gp100:154-162 peptide vaccine

A peptide consisting of amino acid residues 154 through 162 of the melanoma-melanocyte antigen gp100. Vaccination with gp100:154-162 peptide may enhance tumor-specific T-cell immunity. gp100 antigen is a self-antigen expressed by melanocytes, pigmented retinal cells, and most melanoma lesions and is recognized via class I and II HLA-restricted mechanisms.

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Source(s):

The Web site of the National Cancer Institute (http://www.cancer.gov/)

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