gp100 antigen

Definition / meaning of gp100 antigen

A melanoma-associated antigen. When administered in a vaccine formulation, gp100 antigen may stimulate a cytotoxic T cell HLA-A2.1-restricted immune response against tumors that express this antigen, which may result in a reduction in tumor size.

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Source(s):

The Web site of the National Cancer Institute (http://www.cancer.gov/)

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