GM2-KLH vaccine

Definition / meaning of GM2-KLH vaccine

A cancer vaccine consisting of GM2 ganglioside, a melanoma-specific antigen, conjugated with the immunostimulant keyhole limpet hemocyanin. Vaccination with GM2-KLH vaccine may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against GM2 ganglioside-expressing melanoma cells, resulting in tumor growth inhibition.

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Source(s):

The Web site of the National Cancer Institute (http://www.cancer.gov/)

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