F-18 16 alpha-fluoroestradiol

Definition / meaning of F-18 16 alpha-fluoroestradiol

A radiopharmaceutical consisting of an estradiol analogue radiolabeled with the positron-emitting isotope fluorine F 18. F-18 16 alpha-fluoroestradiol is actively taken up in tumor cells expressing the estrogen receptor (ER), allowing visualization of ER-positive tumor cells with positron emiision tomography (PET). Uptake of this agent depends upon the ER status of target tissues.

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Source(s):

The Web site of the National Cancer Institute (http://www.cancer.gov/)

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