epratuzumab

Definition / meaning of epratuzumab

A recombinant, humanized monoclonal antibody directed against CD22, a cell surface glycoprotein present on mature B-cells and on many types of malignant B-cells. After binding to CD22, epratuzumab’s predominant antitumor activity appears to be mediated through antibody-dependent cellular cytotoxicity (ADCC).

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Source(s):

The Web site of the National Cancer Institute (http://www.cancer.gov/)

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