epratuzumab

Definition / meaning of epratuzumab

A recombinant, humanized monoclonal antibody directed against CD22, a cell surface glycoprotein present on mature B-cells and on many types of malignant B-cells. After binding to CD22, epratuzumab’s predominant antitumor activity appears to be mediated through antibody-dependent cellular cytotoxicity (ADCC).

Listed under:

Find More About 'epratuzumab'

Source(s):

The Web site of the National Cancer Institute (http://www.cancer.gov/)

Leave a Comment

*

This site uses Akismet to reduce spam. Learn how your comment data is processed.