epothilone D

Definition / meaning of epothilone D

A natural polyketide compound isolated from the myxobacterium Sorangium cellulosum. Also known as desoxyepothilone B, epothilone D binds to tubulin and inhibits the disassembly of microtubules, resulting in the inhibition of mitosis, cellular proliferation, and cell motility.

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Source(s):

The Web site of the National Cancer Institute (http://www.cancer.gov/)

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