eflornithine hydrochloride ointment

Definition / meaning of eflornithine hydrochloride ointment

An ointment formulation of the hydrochloride salt of an ornithine decarboxylase (ODC) inhibitor with hair-growth inhibitory and potential chemopreventive activities. When administered topically, eflornithine irreversibly inhibits skin ODC activity, thereby inhibiting the synthesis of polyamines; inhibition of polyamine synthesis may result in diminished hair growth and epidermal cell turnover.

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Source(s):

The Web site of the National Cancer Institute (http://www.cancer.gov/)

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