Cancer has spread (1) through the muscle layer of the colon and/or rectal wall to the serosa (outermost layer) of the colon and/or rectal wall; or (2) through the serosa of the colon and/or rectal wall but has not spread to nearby organs; or (3) through the serosa of the colon and/or rectal wall to nearby organs. Also called stage II colorectal cancer.
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