doxycycline hyclate

Definition / meaning of doxycycline hyclate

The hyclate salt of the synthetic, broad-spectrum tetracycline doxycycline with antimicrobial activity. Doxycycline binds reversibly to the 30S ribosomal subunit and possibly to the 50S ribosomal subunit, blocking the binding of aminoacyl-tRNA to the mRNA-ribosome complex, which results in an inhibition of bacterial protein synthesis. In addition, this agent may inhibit collagenase activity.

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Source(s):

The Web site of the National Cancer Institute (http://www.cancer.gov/)

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