dolasetron mesylate

Definition / meaning of dolasetron mesylate

An indole derivative with antiemetic activity. As a selective serotonin receptor antagonist, dolasetron mesylate competitively blocks the action of serotonin at 5HT3 receptors, resulting in suppression of chemotherapy- and radiotherapy-induced nausea and vomiting.

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Source(s):

The Web site of the National Cancer Institute (http://www.cancer.gov/)

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