didemnin B

Definition / meaning of didemnin B

A cyclic depsipeptide extracted from the Caribbean tunicate Trididemnum cyanophorum. Didemnin B activates caspase, thereby inducing apoptosis, and prevents eukaryotic elongation factor 2 (eEF-2)-dependent translocation, thereby inhibiting protein synthesis. This agent also has immunosuppressive and antiviral properties.

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Find More About 'didemnin B'

Source(s):

The Web site of the National Cancer Institute (http://www.cancer.gov/)

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